LL-37
LL-37 is a 37-amino acid antimicrobial peptide (AMP) belonging to the cathelicidin family. In biochemical research, it is studied for its multifaceted role in the innate immune response, including its ability to neutralize lipopolysaccharides (LPS) and promote wound healing pathways. Laboratory investigations often center on its antimicrobial properties and its influence on cell migration.
Biological Functions
- Antimicrobial defense: Exhibits broad-spectrum activity against bacteria, fungi, and viruses by disrupting microbial cell membranes.
- Immunomodulation: Regulates inflammatory responses, recruits immune cells, and interacts with various toll-like receptors.
Research and Medical Interest
- Resistant infections: Studied for potential therapeutic use against multidrug-resistant bacterial strains and biofilm disruption.









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